• Introduction Enzymes have higher selectivity specificity and

  2020-01-08

  

  Introduction Enzymes have higher selectivity, specificity and efficiency than chemical catalysts. Due to their properties and their green chemistry, biocatalysts are widely used in food, textile and pharmaceutical industry [1], [2]. A high efficient biocatalyst for industrial applications must be s

• A comparative analysis of the cleavage activity of different

  2020-01-08

  

  A comparative analysis of the cleavage activity of different forms of the BoNT/A endopeptidase in reduced conditions with SNAPtide and full-length SNAP-25 substrate is summarized in Fig. 5, Fig. 6. The BoNT/A LC was found to be the most active against SNAPtide, a small peptide segment of the SNAP-25

• Data presented herein suggest that competent IL BP productio

  2020-01-07

  

  Data presented herein suggest that competent IL-18BP production in epithelial JIB-04 is implemented by epigenetic means based on demethylation of a single CpG site at −45 bp/−44 bp (CpG2) of the human IL18BP promoter. In contrast, retarded IL-18BP production in monocytic cells associates with CpG2

• The oxidation of the lipid

  2020-01-07

  

  The oxidation of the lipid fraction of meat is an extremely complex process because of the high sensitivity of oxidation products to decomposition, their reactions with other components, the complex effect of catalysts and the presence of antioxidants. These changes are the main cause of limited she

• The need for dedicated DAPT

  2020-01-07

  

  The need for dedicated DAPT updates is well justified by the large amount of data and new information generated in the field over the past few years. As expected, the ACC/AHA and ESC updates contain large areas of overlap as well as some differences. Differences were largely explained by the differe

• Carbonization and decarbonation are two different phases in

  2020-01-07

  

  Carbonization and decarbonation are two different phases in the decomposition of rice husk. Silica in RHA melts around 1440°C [5]. Burning of rice husk at temperature lower than 800°C produces reactive amorphous silica which contains approximately 90% silica, whereas above this temperature some crys

• A possible explanation for these observations has been provi

  2020-01-07

  

  A possible explanation for these observations has been provided by a recent study showing that EWS-FLI-1 increases the Skp2-mediated 26S proteasome degradation, decreasing p27 protein stability and preventing cell senescence [42]. Mechanism of action of EWS-FLI-1 Molecular analysis has revealed

• br Conflict of Interest br Acknowledgements Marques F was su

  2020-01-07

  

  Conflict of Interest Acknowledgements Marques F. was supported by the Foundation for Science and Technology (FCT), Portugal, Grant UMINHO/BI/35/2012. This work was supported by FCT by the Project PTDC/AGR-AAM/70418/2006. Introduction β-methylamino-l-alanine (BMAA) exposure has long been as

• In cancer interactions between the transformed cancer cells

  2020-01-07

  

  In cancer, interactions between the transformed cancer VUF 11207 fumarate receptor and other cell types recruited to the tumor are important. Tumor associated macrophages provide cancer cells with a suitable low-grade inflammatory milieu including growth promoting factors. Our results suggest a nove

• Cholesterol homeostasis is maintained through a tight

  2020-01-07

  

  Cholesterol homeostasis is maintained through a tight regulation between endogenous de novo synthesis, dietary absorption, utilization and excretion of bile salts. The SB 204990 of cholesterol from the intestine constitutes the central part of cholesterol homeostasis in the body [41]. In particular

• Presumably LBPs have health promoting activities such

  2020-01-07

  

  Presumably, LBPs have health-promoting activities, such as antioxidant, immune regulation, anti-stress, anticancer, neuroprotective and antidiabetic activities [[7], [8], [9], [10], [11]]; LBPs can improve the whole-body health status of mice and stimulate the expressions of IL-2, IL-12 and TNF-α, w

• br Conclusions Cereal seeds like the seeds of

  2020-01-07

  

  Conclusions Cereal seeds, like the seeds of all plants, are responsible for the development, protection, dispersal, and nutrition of the next generation. Moreover, cereal caryopses have a high nutritional value for humans and animals. The stable and proper growth of cereal seeds is made possible

• On the opposite side sPLA X has also been

  2020-01-06

  

  On the opposite side, sPLA2-X has also been implicated in the pathology of cancer [167,168]. Human sPLA2-X induces lipid droplet formation in Ras-driven MDA-MB-231 triple-negative breast cancer toremifene synthesis and promotes their survival during nutrient stress. It acts through the products of

• In the past few years we and others

  2020-01-06

  

  In the past few years we and others have reported that GLP-1 may also be secreted by sub-populations of alpha A-366 in human pancreatic islets (Marchetti et al., 2012, Ellingsgaard et al., 2011), which could contribute to beta cell function and survival (Marchetti et al., 2012, Ellingsgaard et al.,

• br Ubiquitin ligases Ubiquitin ligases are

  2020-01-06

  

  Ubiquitin ligases Ubiquitin ligases are categorized into different 2750 sale based on their specific structural configuration and the composition of subunits—HECT (homologous to E6-AP1 (E6-associated protein 1) carboxy-terminus)-type, RING (really interesting new gene)-finger-type, U-box-type, o

14376 records 891/959 page Previous Next First page 上5页 891892893894895 下5页 Last page