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As a support chitosan presents interesting
2020-02-28

As a support, chitosan presents interesting characteristics that reinforce its great potential for enzyme immobilization [18,19]. Firstly, it is produced from renewable natural sources in addition to being biodegradable and water insoluble [20,21]. Also, the main peculiarity in the chitosan structur
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br Experimental Procedures br Author Contributions br Acknow
2020-02-27

Experimental Procedures Author Contributions Acknowledgments Introduction Germinal centers (GCs) form in secondary lymphoid organs of vertebrates in response to challenge with T-cell-dependent antigens. After extrafollicular and follicular interactions with cognate antigen and T helper c
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br Acknowledgments We thank our colleagues who have contribu
2020-02-27

Acknowledgments We thank our colleagues who have contributed to our understanding of the methylergometrine and the structure and function of APC/C, and apologize to those whose work we were unable to cite here. We thank J. Rajan Prabu for making the movies showing APC/C conformational changes. O
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br Results and Discussion br Conclusions
2020-02-27

Results and Discussion Conclusions Based on their common NTP pyrophosphatase activity, similar size of the catalytic domains, and the conservation of glutamate residues, it was assumed previously that the MazG and HisE families were related to MutT and other Nudix family hydrolases (see Zhang
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The following are the supplementary data
2020-02-27

The following are the supplementary data related to this article. Acknowledgments Introduction Cyclooxygenases metabolize arachidonic 94535 mg to five primary prostanoids, PGE2, PGF2, PGI2, TXA2 (TX), and PGD2. These lipid mediators interact with specific members of a family of distinct G-pr
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In Fig results of this experiment are shown as the
2020-02-27

In Fig. 1 results of this experiment are shown as the contour plots of endopeptidase activity. Optimal for the enzyme production by this strain concentrations of peptone and inorganic phosphate were found to be 24 and 0.3g/l, respectively. For specific activity, the optima close to those for glutamy
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br Material and methods br Results br Discussion
2020-02-27

Material and methods Results Discussion Isolated Cap Firefly Luciferase mRNA have several potential advantages over other in-vitro approaches, such as expression of properties similar to their site of origin including the possibility of bidirectional transmembrane transport and exposure. F
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Concholepas concholepas our model species for
2020-02-27

Concholepas concholepas, our model species for this study, is a marine gastropod found along the Chilean coast that has become commercially important [25], [26], [27]. Until now, the main focus of immunology related to C. concholepas is the production of a novel hemocyanin that has been useful for
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br Conflicts of interest br Financial support NZ
2020-02-27

Conflicts of interest Financial support NZ is an Established Investigator of the Dutch Heart Foundation (2013T111) and is supported by an ERC Consolidator grant (617376) from the European Research Council and by a Vici grant from the Netherlands Organization for Scientific Research (NWO; 91818
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br Author Contributions br Acknowledgments br Introduction O
2020-02-27

Author Contributions Acknowledgments Introduction Osteoporosis is a common bone disease that frequently leads to disruption of the alveolar and systemic bones with age. Novel osteoanabolic strategies to treat osteoporotic bone loss or augment fracture repair efficiently are desired. Since b
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The totality of evidence from
2020-02-27

The totality of evidence from randomized clinical trials supports the premise that worsening Donitriptan hydrochloride failure is a class effect of DPP-4 inhibitors. A meta-analysis by Verma et al. (54) of 100 randomized controlled clinical trials reported that the use of DPP-4 inhibitors was accomp
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If the unwanted objects detected by OpenComet
2020-02-27

If the unwanted objects detected by OpenComet are manually deleted, and then the DNA (%) in tail is computed, the performance of the present method can be compared more effectively. Therefore, performance of OpenComet is analysed in two ways as Approach 1 and Approach 2. Approach 1, considers the DN
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KSTDs are generally reported to be intracellular enzymes eit
2020-02-27

— Δ1-KSTDs are generally reported to be intracellular enzymes, either soluble or bound to subcellular particles. For instance, the enzymes from C. testosteroni ATCC 11996 and ATCC 17410 [50,90,99], R. equi [29], and N. simplex ATCC 6946 [52] were particulate-bound. On the other hand, the Δ1-KSTDs fr
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br Conclusions Overexpression of DDR might
2020-02-27

Conclusions Overexpression of DDR2 might contribute to tumor progression in lung SQCC, and the T681I mutation we found in this work is an inactivating mutation. There is a possibility that not only activating mutation but also overexpression of DDR2 might be a molecular target for treatment of lu
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Elevated production of cysLTs in asthma and
2020-02-27

Elevated production of cysLTs in Alda 1 and rhinitis in general and aspirin-sensitive disease in particular10, 11, 26, 27 has been implicated in causing epithelial cell activation and excessive mucus secretion, which characterize these diseases.2, 28 It is of particular interest, therefore, that we
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