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In chicken ovary the adiponectin gene was
2023-10-11
In chicken ovary, the adiponectin gene was found to be mainly expressed in theca cells and is suggested to exert a paracrine or autocrine effect on ovarian steroidogenesis (Chabrolle et al., 2007). A limited number of studies have revealed the effect of adiponectin on ovarian steroidogenesis or its
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In pioneering work from Ikeda
2023-10-11
In 2006, pioneering work from Ikeda and colleagues showed that GMF localizes to and regulates the exendin 4 cytoskeleton (see Glossary), and noted its sequence similarity to ADF/cofilin[11]. In 2009, the structure of GMF [6] was solved, revealing it to be a bona fide member of the actin depolymerizi
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Aminoallyl-dUTP This raises an important question May
2023-10-10
This raises an important question: May the lack of ethnolinguistic theories and of explicit references to language be related to the lack of contact with other groups and their languages? For the past few centuries at least, the Aché seem to have been culturally and linguistically isolated (Hill and
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The present study has several limitations First the results
2023-10-10
The present study has several limitations. First, the results were obtained using RAW264.7 cells, which are derived from BALB/c mice infected with the Abelson leukemia virus (Raschke et al., 1978). However, these cells, which are a commonly used mouse macrophage cell line, show properties similar to
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For these reasons the role played by autophagy in
2023-10-10
For these reasons, the role played by autophagy in environmental neurotoxicity is not always easily determinable. Indeed, although the neuroprotective role of autophagy has been shown by several studies, sometimes induction of autophagy was associate with deleterious effects (Glick et al., 2010, Sri
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The ambiguity surrounding the role played by the LOXs
2023-10-10
The ambiguity surrounding the role played by the 15-LOXs in malignant biological processes stems also from the limitations of current animal models, and especially the usage of its 12/15-LOX murine homolog, which can also catalyze the production of 12-HETE. Indeed, the proinflammatory effect of 12-H
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The distribution and subcellular localization
2023-10-10
The distribution and subcellular localization differs between the subtypes of mGlu receptors. Most mGlu receptors are broadly expressed in the brain, except for mGlu6, which is restricted to the retina. Some mGlu receptors are additionally found in glial cells, such as mGlu3 and mGlu5 (Aronica et al
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Plasma apelin levels predict the major cardiovascular
2023-10-10
Plasma apelin levels predict the major cardiovascular event after percutaneous coronary intervention in patients with ST elevation myocardial infarction (STEMI), and adverse events are higher in patients with lower plasma apelin levels [75]. Apelin and its receptor are markedly upregulated in the he
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HMGN proteins are subject to extensive
2023-10-10
HMGN proteins are subject to extensive post-translational modifications which influence both their mode of binding to DRB australia and their functional activity. Like the other HMG protein families, HMGNs are substrates for many of the same enzymes that modify histone proteins (review in [175]). T
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br Implementation of sacubitril valsartan into clinical
2023-10-10
Implementation of sacubitril/valsartan into clinical practice Following on from the results of PARADIGM-HF, sacubitril/valsartan was given regulatory approval for use in patients who conform to the main inclusion criteria of the trial; NYHA functional class II–IV, reduced left ventricular ejectio
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Consistent with the in vitro results memantine
2023-10-10
Consistent with the in vitro results, memantine ameliorated Aβ-induced cytotoxicity in rat primary cortical cultures. Studies reported that memantine protected neurons against the damage caused by aggregated Aβ40 or Aβ42 oligomers in vivo[26], [27]. These results suggest that, in addition to its neu
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br Conflict of interest statement
2023-10-10
Conflict of interest statement Introduction Tanshinone IIA (Tan IIA) is a major active component of Salvia miltiorrhiza (S. miltiorrhiza), a well-known Chinese traditional medicine that is used for the treatment of cardiovascular and cerebrovascular diseases [1]. Tan IIA exhibits diverse pharm
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Outro grupo de trabalho analisou pares de g meos dinamarques
2023-10-10
Outro grupo de trabalho analisou 8.503 pares de gêmeos dinamarqueses de meia‐idade (nos Phosphocreatine disodium salt synthesis de cognição comparados com os que não sofreram qualquer intervenção, no entanto os autores consideram a diferença como um efeito de tamanho negligenciável. Na análise intra
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br Discussion Missense mutations transversions of
2023-10-10
Discussion Missense mutations (transversions) of the first nucleotide of the phenylalanine colorimetric assay mg at position 1174 (F1174) of the anaplastic lymphoma kinase gene can result in substitutions to leucine or valine (F1174L/V) while missense mutation (transversion) of the second nucleo
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br Acknowledgements Dr Paul J Gasser
2023-10-10
Acknowledgements Dr. Paul J. Gasser is supported by the National Institutes of Health (grant number R01DA032895), and the Charles E. Kubly Mental Health Research Center. Dr. Christopher A. Lowry is supported by the National Institutes of Health (grant number R21 MH116263), the Department of the N
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